Residual titanium dioxide (TiO2) can certainly pose issues due to it's nature in the presence of heat. To remove TiO2 from tanks using CIP sprayballs, it is important to use.
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Solvent cleaning and wettability of technical steel and titanium
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Cleaning Titanium Dioxide from Tanks - TechNotes – Critical
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Solvent cleaning and wettability of technical steel and titanium