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The Vehicle Routing Problem (VRP) is a highly investigated logistics problem. VRP can model in-plant and out-plant material handling or a whole supply chain. The first Vehicle Routing Problem article was published in 1959 by Dantzig and Ramser, and many varieties of VRP have appeared since then. Transport systems are becoming more and more customized these days, so it is necessary to develop a general system that covers many transport tasks. Based on the literature, several components of VRP have appeared, but the development of an integrated system with all components has not yet been completed by the researchers. An integrated system can be useful because it is easy to configure; many transportation tasks can be easily modeled with its help. Our purpose is to present a generalized VRP model and show, in the form of case studies, how many transport tasks the system can model by including (omitting) each component. In this article, a generalized system is introduced, which covers the main VRP types that have appeared over the years. In the introduction, the basic Vehicle Routing Problem is presented, where the most important Vehicle Routing Problem components published so far are also detailed. The paper also gives the mathematical model of the generalization of the Vehicle Routing Problem and some case studies of the model are presented.